Research Papers
Welcome to our collection of research papers in the field of magnetogenetics. Explore our findings and discoveries that contribute to the advancement of wireless neuromodulation technology.
In vivo magnetogenetics for cell-type-specific targeting and modulation of brain circuits
Cell-type-specific magnetogenetics enables precise, non-invasive, and long-term wireless control of deep-brain neural activity and behavior using nanomagnetic actuators to activate genetically targeted ion channels.
Nanoscale Magneto-mechanical-genetics of Deep Brain Neurons Reversing Motor Deficits in Parkinsonian Mice
Magneto-mechanical-genetic (MMG) stimulation uses magnetic nanostructures to non-invasively and wirelessly activate Piezo1 channels in subthalamic neurons, providing implant-free, cell-specific deep brain stimulation that effectively alleviates motor symptoms in Parkinson’s disease mice.
Non-contact long-range magnetic stimulation of mechanosensitive ion channels in freely moving animals
The m-Torquer system delivers long-range, piconewton-scale magnetic torque to Piezo1-expressing neurons, enabling reproducible, non-invasive, and cell-specific neuromodulation in freely moving animals.